Editorial
Editorial
COVID-19 epidemic process in the Russian Federation: determinants and manifestations
Annotation
In case of a new coronavirus infection, a constant assessment of the epidemic process manifestations and their determinants is important for the development of preventive and anti-epidemic measures appropriate to the real situation. Aim. A dynamic assessment of the
Original researches
The incidence of tuberculosis in Russian Federation before and during the COVID-19 pandemic
Annotation
The COVID-19 pandemic had a devastating impact on the implementation of anti-tuberculosis measures in Russian Federation, and first of all, the organization of screening aimed at early detection of tuberculosis among the population. This led to the stable dynamics loss of
Influence of bedaquiline on the course of HIV-infection combined with tuberculosis
Annotation
Bedaquiline has an immunomodulatory effect by acting on macrophages, which raised concerns that bedaquiline could provoke progressing of HIV infection. The aim was to study the possible influence of bedaquiline on the duration of HIV infection in patients with HIV-associated
Possibilities for early prediction of COVID-19 outcomes in hospitalized patients
Annotation
Assessment of the disease prognosis at an early stage of the COVID-19 infectious process, in the first days after hospitalization, based on research methods available for practical health care, will improve the routing and management of patients with a new coronavirus
Variability of time trends of glycemia and outcomes of COVID-19 associated pneumonia in patients with comorbid diseases
Annotation
Unfavorable outcomes are often noted among intensive care units (ICU) patients with COVID-19 associated pneumonia and comorbid diseases. Diabetes status and elevated admission blood glucose levels are their important predictors. Aim. To evaluate the influence of time trends
The neuropilin-1 content in the serum of patients with community-acquired pneumonia and COVID-19
Annotation
There is information about the role of the SARS-CoV-2 virus in the development of damage to the central and peripheral nervous system, violation of the blood-brain barrier integrity, which uses the transmembrane protein neuropilin- 1 ( NRP-1 ) as an entrance gate. The aim of
The effectiveness of the combined use of specific and nonspecific COVID-19 preventive measures
Annotation
Prevention of SARS-CoV-2 infection among medical and healthcare workers remains to be one of the top public health priorities. Objective. To assess the effectiveness of the combined use of vaccine and recombinant interferon alpha-2b-based medicine (Grippferon ® ) for
Features of management of patients with COVID-19 and secondary immunodeficiency in real clinical practice
Annotation
Aim – description of the clinical course and management tactics of immunocompromised patients with COVID-19 in real clinical practice. Material and methods. We present the results of dynamic observation and curation of two patients with COVID-19, which developed
Causes of adverse outcomes in children with perinatal contact for HIV infection
Annotation
The HIV pandemic is a serious problem for society and healthcare systems, both worldwide and in Russian Federation. Prevention of perinatal HIV transmission is an integral part of prevention programs and its effectiveness depends on the completeness and timeliness of its
HIV-1 resistance to first-line antiretroviral therapy
Annotation
The aim of the study was to analyze the resistance of HIV-1 to the first-line antiretroviral drugs in HIV-infected people and adherence to antiretroviral therapy (ART) regimens with various genetic barriers to drug resistance. Material and methods. A study cohort included
Hepatitis B vaccination coverage among health care workers in Mongolia
Annotation
Since healthcare workers are at high risk of occupational exposure, hepatitis B virus ( HBV ) infection is a challenging occupational health problem. The annual estimated proportion of healthcare workers (HCWs) exposed to HBV globally is 5.9%, corresponding to an estimated
Clinical and immunological aspects of the course of chronic viral hepatitis B with delta infection in pregnant women
Annotation
In the period from 2019 to 2021, an open prospective study was conducted with the participation of 88 pregnant women aged 18 to 45 years who were on dispensary registration in a polyclinic and inpatient treatment in 1 city infectious diseases hospital in Tashkent with a
Chronic mucocutaneous candidiasis in children with STAT1 gene mutations
Annotation
Purpose. The analysis of clinical features of chronic mucocutaneous candidiasis (CMC) for children with mutations in the STAT1 gene mutations. Material and methods. The retrospective and prospective analysis of the clinical course of chronic mucocutaneous candidiasis was
Reviews
Achievements in the study of molecular biological characteristics of different species within the genus Borrelia
Annotation
This review presents in chronological order the study results on the bacterial genome of Spirochaetaceae family representatives within the genus Borrelia . The main achievements of the application of the latest molecular biology methods in the study of the Borrelia genome by
On the prospective use of bacteriophages in the treatment of cystic fibrosis
Annotation
According to the clinical guidelines for the treatment of cystic fibrosis (CF) used in the Russian Federation, antibiotic therapy is recommended for all patients with pulmonary manifestations of CF. Although, prolonged treatment with the antibiotics may lead to the
Continuing medical education
Revaccination against COVID-19: the current state of the problem (lecture preparation material)
Annotation
The article summarizes and systematizes the results of studies conducted in different countries on booster vaccination against COVID-19 as well as reflects data on the effectiveness, reactogenicity and immunogenicity of various vaccines used as boosters of the population
Diagnosis, treatment and follow-up of patients with alveolar echinococcosis (lecture preparation material)
Annotation
Human alveolar echinococcosis (AE) is a zoonotic natural anthropurgic parasitic disease with a fecal-oral mechanism of pathogen transmission, caused by the larval stage (methacestode) of the tapeworm Echinococcus multilocularis . The frequency of registration and geographic
Practitioner’s consult
Toxic myocarditis with a fatal outcome in a child with hemorrhagic fever with renal syndrome
Annotation
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral zoonotic natural focal seasonal disease with different severity options. At the same time, the difficulty of diagnosing this infection is determined by the absence of specific clinical and morphological
Clinical tests
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