Editorial
Analysis of the manifestations of the COVID-19 epidemic process in the territory of the Moscow agglomeration for the period 2020–2022
Abstract
During the pandemic spread of SARS-CoV-2 infection, which rapidly took over different countries and continents, some experience has been gained in the epidemiological diagnosis of this new infectious disease. The study of the features of the manifestations of the COVID-19
Original researches
Dynamics of the incidence of occupational coronavirus infection COVID-19 and mortality from it of medical workers of healthcare institutions of the Federal Medical-Biological Agency of the Russian Federation
Abstract
Medical workers are at the forefront of the fight against COVID-19 coronavirus infection, being at higher risk of contracting this disease and, as a result, becoming a possible source of infection for patients and other workers. In some works, they report on the occupational
The impact of influenza vaccination on the prevention of acute respiratory infections
Abstract
The aim of the study was to assess the impact of influenza vaccination on the amount and severity of episodes of acute respiratory infections (ARI) in children and adults. Material and methods. A retrospective epidemiological study was conducted from August 2023 to June 2024
Clinical and immunological effectiveness assessment of the intranasal recombinant interferon alpha-2b medicine in children with obstructive laryngitis and epidemically significant respiratory infections
Abstract
Objective – to assess the effectiveness of topical interferon-alpha-based treatment of influenza and coronavirus infections in children with acute obstructive laryngitis. Material and methods. A total of 87 children (aged 1 to 6 years) with obstructive laryngitis
The structure of fatal outcomes in HIV infected patients during hospitalization in Moscow hospitals from 2015 to 2019
Abstract
An increase in the number of deaths in the cohort of HIV infected people of working age leads to social, demographic and economic losses. The aim of the study was to analyze the structure of death causes of inpatients with HIV infection for the period from 2015 to 2019 in
Retrospective analysis of the epidemic situation for HIV, tuberculosis and coinfection of HIV/tuberculosis
Abstract
The evolution of the HIV epidemic in many countries has led to a significant increase in the detection of HIV/tuberculosis (TB) co-infection. The aim. Analysis of the dynamics of the main indicators characterizing the epidemic situation of tuberculosis, HIV infection and
Species diversity of fungi isolated from patients with cystic fidosis
Abstract
Cystic fibrosis (CF) is a genetic autosomal recessive disease caused by a mutation in the cystic fibrosis transmembrane conductance regulator ( CFTR ) gene and manifests itself as damage to the exocrine glands, mainly the respiratory and digestive systems. Chronic lower
Immunoprophylaxis of children: opinion and awareness of parents
Abstract
The importance of vaccination is beyond doubt. However, some people express doubts about vaccinations or completely abandon them. In this regard, the issues of parents’ awareness of the need to vaccinate their children require study. The purpose of the study is to
Reviews
Modern possibilities of etiotropic and pathogenetic therapy for respiratory infections
Abstract
For many years, acute respiratory viral infections have occupied a leading place both in the structure of infectious diseases and in the ranking of infectious diseases (without tuberculosis and HIV infection) in terms of economic damage in the Russian Federation. The purpose
Umifenovir in China: a review of scientific and clinical data
Abstract
Influenza and acute respiratory viral infections (ARVI) show high seasonal activity among the population of any age, especially in developing countries. Clinical guidelines for the treatment of ARVI include several classes of drugs and, first of all, recommend the use of
The role of pan-genotypic direct acting antivirals for the treatment of chronic hepatitis C virus infection
Abstract
The aim – analysis of modern publications describing the effectiveness and adverse events in the treatment of chronic hepatitis C with modern pan-genotypic drugs. Material and methods. The search for publications was carried out in the electronic libraries PubMed and
A comprehensive review on poultry-origin bacterial pathogens Salmonella and Campylobacter as global public health burden
Abstract
Salmonella and Campylobacter are gram-negative bacteria that are considered as food-borne pathogens contributing to about 1/3 of food-borne diseases globally by the World Health Organization. Salmonellosis and Campylobacteriosis are two major food-borne diseases of public
Hydatidous echinococcosis of the liver and lungs: diagnostic and therapeutic aspects
Abstract
The purpose is to analyze and systematize data on the problem of diagnosis and therapy of single-cystic (cystic, hydatidous) echinococcosis of the liver and lungs. Material and methods. A search of scientific literature for the period 1986–2022 was conducted in the
Continuing medical education
Modern aspects of antiviral therapy for hepatitis C
Abstract
Viral hepatitis C is an inflammatory infectious disease of the liver, which is an important medical and social health problem. Currently, the standard of care for hepatitis C is the administration of highly effective direct-acting antiviral drugs (DAAs). The aim of the
Bacteriophages: past and present in the laboratory diagnosis of plague
Abstract
The purpose of this review was to analyze the literature on plague and pseudotuberculous bacteriophages and their significance in the laboratory diagnosis of plague. The historical issues of the formation of ideas about bacteriophages related to the outstanding scientific
Practitioner’s consult
Foodborne botulism: a clinical case
Abstract
The prevalence of home canning is the reason for the occurrence of botulism throughout the world. Botulism is difficult to diagnose due to the polymorphism of clinical manifestations at the very beginning of the disease. An acute intestinal infection or neurological
Clinical case of multiple complications of pregnancy and puerperium in patient, infected COVID-19
Abstract
The peculiarities of management of pregnancy and childbirth in patients with a new coronavirus infection COVID-19, the mechanisms of the formation of complications, the possibilities of their prevention and treatment are an urgent problem of modern medicine. Objective to
Clinical efficacy of using bacterial lysates in treatment of recurrent respiratory tract infections in children
Abstract
The peculiarities of the development of the immune system of children acute respiratory tract infections (ARTIs) may result in complications (otitis, sinusitis, tonsillitis), which often worsens the prognosis of the disease and lengthens the treatment process. A special
The impact of infection on micronutrient status: the role of vitamins and trace elements in defense against infection
Abstract
On March 23, 2024, in Moscow, an Expert Council was held to discuss the relationship between the infectious process and changes in micronutrient status. Vitamins and minerals play a crucial role in maintaining adequate immune function at all levels. The influence of vitamins
Resolution of the scientific symposium «Antimicrobial shield» – a strategy for effective antimicrobial therapy of complicated and uncomplicated diseases of the upper respiratory tract and ENT-organs in adults and children
Abstract
As a rule, the trigger mechanism of the upper respiratory tract inflammatory diseases are respiratory viruses or their associations with bacteria. Synergy of phage and antibiotic shows significantly higher efficiency than monotherapy with antibiotics or bacteriophages in
Expert council «Control of virus-induced respiratory tract inflammation»
Abstract
At an expert panel, leading specialists discussed modern approaches to controlling virus-induced inflammation of the respiratory tract, caused by various respiratory infections, including acute respiratory viral infections, influenza, and COVID-19. During the meeting, key
The use of acetylsalicylic acid medications in the management of common cold and influenza in adults: safety implications
Abstract
Acetylsalicylic acid (ASA) has retained its clinical significance for more than 125 years following its discovery. Extensive clinical experience and research have elucidated its wide-ranging applications as an antiplatelet, analgesic, and anti-inflammatory agent, presenting
Clinical tests
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