Current issue
4 . 2022
Content
Editorial

Editorial

Abstract
Editorial

Olokizumab reduces the risks of death in hospitalized patients with moderate and severe COVID-19

Abstract
Aim – to evaluate the efficacy and safety of olokizumab in hospitalized patients with moderate to severe coronavirus disease COVID-19. Material and methods. A multicenter non-interventional retrospective study of olokizumab treatment in hospitalized patients with COVID
Original researches

Prognostic criteria for the development of severe clinical forms of COVID-19 in medical organization workers

Abstract
Employees of medical organizations are one of the risk groups for infection with a new coronavirus infection (COVID-19), including with the development of severe clinical forms. The aim of the study was to analyze the clinical manifestations of a new coronavirus infection in

Clinical and laboratory manifestations and pathological anatomical picture of a severe course of a new coronavirus infection COVID-19 with a fatal outcome

Abstract
Aim – to study the clinical and laboratory manifestations of a severe course of COVID-19 in a lethal outcome with an assessment of the pathomorphological picture based on autopsy material. Material and methods. A retrospective analysis of demographic, clinical and

The use of neutralizing monoclonal antibodies against SARS-CoV-2 in hemodialysis patients

Abstract
Patients with end-stage kidney disease undergoing hemodialysis have one of the highest COVID-19 mortality rates. The use of innovative methods capable of optimizing their treatment outcomes is important for clinical practice. Aims – to investigate the efficacy and

Study of cases of Pseudomonas aeruginosa bacteria in patients with severe COVID-19

Abstract
Pseudomonas aeruginosa can cause severe nosocomial infections and sepsis, especially in immunocompromised comorbid patients. The purpose of the study was to assess the frequency, clinical course, and the possibility of antimicrobial therapy for bloodstream infections caused

Risk factors for severe and prolonged acute respiratory viral infections in young patients

Abstract
Acute respiratory infections remain one of the most common infectious diseases, which are mostly mild, and there is also a possibility of developing severe forms of the disease. The article considered the possibilities of early prediction of severe course of acute

Assessment of knowledge and attitudes of the adult population of the Republic of Bashkortostan to the prevention of influenza and acute respiratory viral infection

Abstract
According to WHO, seasonal influenza epidemics occur annually in the world, during which from 3 to 5 million cases of influenza are detected. In the Republic of Bashkortostan for the period 2015–2019, the increase in the incidence of influenza amounted to 330%. Despite

Rational approach to the therapy of patients with liver cirrosis at the outcome of chronic hepatitis C

Abstract
Liver cirrhosis ranks 5th in the structure of diseases that reduce life expectancy in people of working age in Russia. The mortality rate for 1 year can reach 80% with decompensation of cirrhosis. Objective – assessment of clinical, laboratory and instrumental data in

Diversity of circulating rotavirus strains before and after the introduction of rotavirus vaccine

Abstract
Every year, rotaviruses cause more than 137 million cases of acute gastroenteritis worldwide, of which up to 592,000 are fatal. The aim – of the study is to assess trends in the circulation of rotavirus strains in the Republic of Tajikistan before and after the

A new approach to assessing the immunomodulatory and virus-inhibiting activity of medical preparations

Abstract
The effect of interferon on cells is carried out through interaction with specific cellular receptors. Interferon is necessary for the formation of an immune response to an antigenic stimulus, and each antigen is an interferonogen. The presence of monoclonal antireceptor
Reviews

Trace elements: role in the development of severe forms of COVID-19 and the possibility of correction

Abstract
The COVID-19 pandemic has set tasks for health professionals, in particular, related to the rapid diagnosis of the disease and the provision of medical care to patients with a new coronavirus infection. All over the world, scientific work is being carried out on the study of

Use of the drug angiovit in hemorrhagic fever with renal syndrome: evaluation of markers of vascular endothelial damage and kidney disfunction

Abstract
Hemorrhagic fever with renal syndrome (HFRS) is a common natural focal infectious disease in the Republic of Bashkortostan. Most patients are admitted to the clinic later than the 5th day of illness, when etiotropic drugs no longer show sufficient effectiveness, which
Continuing medical education

Contemporary methods of laboratory diagnostics of tuberculosis. The detection of the pathogen and determination its drug sensitivity

Abstract
A reliable diagnostic criterion for tuberculosis is the detection of Mycobacterium tuberculosis in the material received from the patient. The article presents bacterioscopic, bacteriological, molecular genetic methods for the diagnosis of M. tuberculosis with the

Clinical features of bacterial intestinal infections in people over 60 years of age (lecture preparation material)

Abstract
The incidence of intestinal infections has different dynamics in time and space. In all regions of the world, both ups and downs in the incidence are recorded among all age groups of the population. About 2.5 billion cases of acute intestinal infections are registered every
Practitioner’s consult

Approaches to vaccination against coronavirus infection in patients with autoimmune inflammatory rheumatic diseases

Abstract
The problem of COVID-19 vaccination in patients with autoimmune inflammatory rheumatic diseases is discussed. There is an increased risk of viral infections in these patients. Attending physicians should provide patients with rheumatic diseases with complete information

A case of meningococcal pneumonia complicated by bilateral pleurisy, pericarditis

Abstract
A clinical case of a generalized form of meningococcal infection, occurring with bilateral pneumonia and complicated by the development of bilateral pleurisy, pericarditis in a 33-year-old man, is presented. The absence of classical manifestations of the generalized form of

Infectious mononucleosis combined with SARS-CoV-2 infection

Abstract
A clinical analysis of COVID-19 cases combined with acute respiratory diseases is presented. The aim of the study was to analyze clinical and laboratory data of patients with combined COVID–19 infection. In patient A. infected with SARS-CoV-2 without X-ray confirmation
Clinical tests

Clinical tests

Abstract
News

News (# 4, 2022)

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Information

Information

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All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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