Current issue
1 . 2022
Content
Editorial

Dear colleagues, dear friends!

Abstract

Analysis of the possible association of patients’ genetic factors with course of dengue virus infection

Abstract
The aim of the study was to investigate association of genes polymorphisms of the innate immunity and blood clotting system with different courses of dengue fever (DF). Material and methods . The following groups of subjects were formed: dengue hemorrhagic fever (DHF) ( n
Original researches

Mortality rate and case fatality rate of COVID­19 around the world: an adjusted estimation

Abstract
The present study is designed to predict the global adjusted values for mortality rate and case fatality rate of COVID­19 around the world. This study aims – to investigate some of the predictive factors which may affect the mortality rate and case fatality rate

Determination of antibodies to SARS-CoV-2 in patients with coronavirus infection

Abstract
COVID-19, caused by the novel SARS-CoV-2 virus, poses major challenges for global public health. The detection of antibodies in blood serum is one of the important methods for diagnostics of COVID-19 patients. The main aim was to study the dynamics of the appearance of

Results of screening examination of employees of a medical hospital for antibodies to SARS-CoV-2

Abstract
While providing medical care to patients with a new coronavirus infection, medical workers are at risk of developing COVID-19 significantly more often than the general population. In addition to morbidity risks, an important question is the duration of the immune response to

Preliminary analysis of the epidemiological effectiveness of COVID-19 vaccination in the Saratov Region

Abstract
The new coronavirus infection (COVID-19) caused by the SARS-CoV-2 virus continues to spread rapidly worldwide, despite the increased prevention and treatment measures being taken. Vaccination is one of the most cost-effective and effective methods of preventing infectious

Some clinical and epidemiological aspects of the course of COVID-19 in people living with HIV

Abstract
Objective. To describe the clinical and epidemical characteristics of a new coronavirus disease 2019 (COVID-19) in people living with HIV, for HIV infection implies the development of an immunosuppressive condition that may exacerbate the course of COVID-19. Material and

COVID-19: the efficacy and safety of anticoagulant, glucocorticosteroid therapy and metabolic

Abstract
Objective : assessment of the efficacy and safety of the use of anticoagulant, glucocorticosteroid, metabolic therapy in patients with COVID-19 at the inpatient stage of treatment. Material and methods . In February 2021, a prospective, randomized, single-center, continuous

Validation of the russian version of the 4C Mortality Score and prediction of outcomes of severe COVID-19

Abstract
The aim of the study is to validate the Russian version of the 4C Mortality Score scale and evaluate its accuracy in predicting the outcomes of severe COVID-19. Material and methods. The staff of the Center for Validation of International Scales and Questionnaires of the

Differential diagnosis of measles and infectious mononucleosis

Abstract
Differential diagnostic criteria of measles and infectious mononucleosis are presented, which contribute to the early diagnosis of these diseases, timely therapy and anti-epidemic measures. The aim of the study was to identify differential diagnostic criteria for the

Diagnostic value of detection of LAM-antigen of mycobacteria tuberculosis in the urine of patients with HIV infection

Abstract
Tuberculosis, as before, remains one of the main causes of deaths in HIV infected people. The problem of timely diagnosis of tuberculosis is one of the main unsolved health problems. Despite the availability of modern methods for diagnosing tuberculosis, the problem remains

Monoclonal antibodies to the interleukin­-6 receptor in the treatment of COVID-­19 in patients with chronic kidney disease

Abstract
Interleukin­-6 (IL-­6) plays a key role in the pathogenesis of COVID­19, which determines the indications for the therapeutic use of its antagonists. However, data on their effectiveness and optimal timing of appointment are contradictory. The question of the

Features of the course and medical and social aspects of a new coronavirus infection in the Republic of Tajikistan

Abstract
The aim – to assess some medical and social aspects of the epidemic process during the first wave of a new coronavirus infectious disease – COVID-­19 in the Republic of Tajikistan. Material and methods. The retrospective study was conducted on the basis of

Prevention of COVID-19 coronavirus infection with aminodihydrophthalazinedione sodium (Galavit®) in medical staff of the “red zone”: results of the multicenter observational study

Abstract
COVID-hospital healthcare workers belong to a high-risk SARS-CoV-2 infection. The aminodihydrophthala-zinedione sodium (Galavit ® ) belongs to the group of immunomodulatory and anti-inflammatory drugs. It has been shown that aminodihydrophthalazinedione sodium is

Listeriosis and the COVID-19 pandemic

Abstract
Listeriosis is a saprozoonotic infection that occurs when eating foods contaminated with Listeria. Invasive forms of listeriosis can have extremely severe consequences. Respiratory viral diseases predispose to the occurrence of combined viral-bacterial infections. With a
Reviews

Rocio encephalitis

Abstract
Rocio virus is an arthropod borne virus transmitted by mosquitoes, belonging to genus Ochleratus . The reservoir of the virus in nature is sparrows Zonotrichia capensis . The Rocio virus is transmitted through the bite of infected mosquitoes. The epidemic and epizootic cycle

Helicobacter pylori: clinical significance and diagnostic principles

Abstract
Helicobacter pylori is one of the most significant human pathogens. H. pylori causes chronic gastritis in all infected individuals, which can lead to peptic ulcer disease, atrophic gastritis, gastric adenocarcinoma, or gastric MALT lymphoma. Eradication of H. pylori leads to
Continuing medical education

Ricketsiosis (material for the preparation of the lecture)

Abstract
Over the past decades, the problem of infectious diseases accompanied by hemorrhagic syndrome, in particular rickettsial etiology, has become one of the priorities. These diseases are referred to as "emerging" (unpredictable), threatening to complicate the epidemic situation

Continuing medical education: issues of improving the professional level of specialists working with biological agents of groups I—II of pathogenicity

Abstract
The training of highly qualified specialists for working with pathogenic biological agents in the format of continuous medical education requires solving a number of issues. The aim is to assess the possibilities of implementing the basic principles of improving the
Practitioner’s consult

A case of generalized tuberculosis with the development of tuberculous meningoencephalitis in the practice of an infectious disease doctor

Abstract
The article presents a clinical case of generalized tuberculosis with the development of tuberculous meningoencephalitis in a 27-year-old patient. One of the features of this case was the difficulty of confirming the clinical diagnosis when using methods of specific

Challenges and solutions for COVID-19 (extract from Resolution 1 of the General Meeting of the Department of Medical Sciences of Russian Academy of Sciences, dated 12/13/2021)

Abstract
Clinical tests

Clinical cases

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News

News (# 1, 2022)

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All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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