Editorial
Editorial
The effectiveness of three commercially available Bacillus Calmette-Guerin vaccines for the prevention of tuberculosis among children: results of a cohort, controlled, retrospective analysis
Abstract
The study analyzed aggregated national data on Bacillus Calmette-Guerin (BCG) vaccination of newborns against tuberculosis (TB) and information obtained by case-based computer surveillance data for TB in the Republic of Kazakhstan. Over nearly two decades, coverage of
Original researches
Analysis of the main epidemiological indicators of HIV infection and results of multi-year application of antiretroviral therapy (by the materials from the North-West of Russia)
Abstract
The aim of the work is to analyze the effect of ongoing antiretroviral therapy on indicators characterizing the epidemic process of HIV infection. Material and methods. In the course of the analysis, generalized statistical materials were used for the North-West Federal
Comparative characteristics of different types of spontaneous HIV-1 non-progressors
Abstract
The aim - to identify and describe different types of spontaneous HIV-1 non-progressors. Material and methods. We describe the cohort of 31 non-progressors that are under regular medical check-up in Moscow AIDS Center. We identify and characterize 15 elite controllers, 12
Immunological aspects of kidney damage in HIV infection
Abstract
The aim of the study was to assess the role of cellular and cytokine components of the immune response in kidney disease in patients with HIV infection. Material and methods. The study included 40 patients with HIV infection, who were determined by indicators of cellular
Results of treatment of extra articular long bone fractures in patients with HIV-infection
Abstract
A comparative analysis of the results of surgical treatment of 90 HIV-infected and 112 non-HIV-infected patients with extra-articular fractures of the long bones of the limbs was carried out. During the conducted analysis it was noted that HIV-infected patients at the IV-V
Narlaprevir, ritonavir, and sofosbuvir in non-cirrhotic chronic hepatitis C genotype 1 infected patients
Abstract
Aim of investigation - to estimate efficacy and safety of combination of direct-acting antivirus agents narlaprevir/ritonavir and sofosbuvir in patients with chronic hepatitis C. Material and methods. Treatment naive, non-cirrhotic patients with chronic HCV infection (GT1)
Clinical and epidemiological features chronic hepatitis C in children
Abstract
Chronic hepatitis C is a serious pediatric problem. It is known that about 11 million patients with chronic hepatitis C in the world are children under the age of 15. Aim of the study was to study the clinical and epidemiological features of the course of chronic hepatitis C
Dynamic evaluation of the immune system response of children of different ages in Epstein-Barr viral infectious mononucleosis
Abstract
Aim to reveal dynamic assessment of the immune system response in children of different ages in Epstein-Barr viral (EBV) infectious mononucleosis (IM). Material and methods. We conducted the study of 98 children with EBV IM, including a comprehensive immunological
Clinical and pathogenetic significance of metabolic disorders in infectious mononucleosis
Abstract
Aim - the purpose of the work is to reveal the features of the changes of lipid peroxidation processes and cytokine profile indices in patients with infectious mononucleosis of various severity courses in the dynamics of infectious process. Material and methods. The patients
Turning to the question of formation of asymptomatic forms of infection caused by human herpes virus 6 variant B in children
Abstract
Laboratory markers of human herpesvirus 6A and 6B infection are detected with high frequency not only in patients with somatic pathology, but also in apparently healthy people. Up to the present moment mechanisms of occurrence of various forms of infection process
Clinical and epidemiological aspects of enterovirus infection
Abstract
In 2017, the Chelyabinsk region registered an increase in the incidence of enterovirus infection (EVI) caused by enteroviruses ECHO 30h, ECHO 9, Coxsackie A6. The incidence of EVI in 2017 compared to 2016 increased by 7.58 times and amounted to 24.16 per 100 thousand
Socially significant infectious diseases in the Republic of Bashkortostan: state of incidence and mortality rate in 2009-2018
Abstract
The aim of the study is to analyze the level and dynamics of incidence and mortality rate from socially significant infectious diseases in the Republic of Bashkortostan from 2009 to 2018. Material and methods. A retrospective and operational epidemiological analysis was
Differential diagnostics of the Crimean hemorrhagic fever and measles at the modern stage
Abstract
The paper presents modern differential diagnostic criteria for the diagnosis of Crimean hemorrhagic fever caused by the Congo virus (CHF), and measles, allowing timely diagnosis and early adequate therapy. Specific epidemiological signs were identified that could indicate
The composition of the intestinal microbiome as a predictor of gram-negative bloodstream infections in patients receiving hematopoietic stem cell transplantation
Abstract
Currently understanding of pathogenesis of infections in immunosuppressed patients with hematological diseases was based on exogenous infections. In this clinical research paper we show the microbiome-associated factors leading to bloodstream infections in immunosuppressed
Reviews
Development of anatoxin preparations and solution problems of their production in the USSR (material for the preparation of the lecture)
Abstract
The article describes the history of the creation of highly purified concentrated toxoids against anaerobic infections using meatless nutrient media based on modern industrial (in fermenters) technologies.
Continuing medical education
Portfolio of the discipline «infectious diseases» as an alternative of a new educational technology
Abstract
Aim of portfolio - to show the potential of application of a new educational technology "Student's portfolio" of the discipline "Infectious diseases" as one of the evaluation tools provided for by the Federal State Educational Standard of Higher Education. Material and
Clinical tests
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