Current issue
2 . 2019
Viral hepatitis
Content
Editorial

Editorial

Abstract
Original researches

Genetic determination of spontaneous clearance of the hepatitis C virus in representatives of different ethnic groups

Abstract
The present work has determined associative links between polymorphism of genes involved in intracellular signaling of innate immunity responses and the frequency of spontaneous clearance of the virus hepatitis C in representatives of various ethnic groups of people living

Dynamic changes in the prevalence of hepatitis C virus in the general population in the Republic of Sakha (Yakutia) over the last 10 years

Abstract
Aim . To determine the prevalence of hepatitis C virus (HCV) infection among all age groups of conditionally healthy population of the Republic of Sakha (Yakutia) and to analyze its changes over the past 10 years. Material and methods . 1045 samples of blood serum from a

Clinical and epidemiological features and outcomes of viral hepatitis C in ethnic groups of Mongoloids and Caucasians living in cross-border regions of North-East Asia

Abstract
Despite the known success in reducing the incidence of hepatitis C in the world, in the countries of the Asia-Pacific region there is a high level of annual growth in new infections and a high incidence of hepatocellular carcinoma (HCC). These indicators are influenced not

The impact of universal vaccination against hepatitis B on the prevalence of hepatitis D in endemic region

Abstract
Mass vaccination against hepatitis B has led to a decrease in the prevalence of the hepatitis B virus (HBV), as well as to a decrease in the spread of another related pathogen, the hepatitis delta virus (HDV). However, the incidence of hepatitis D persists and, moreover, its

Epidemiology and prevention of community-acquired pneumonia

Abstract
The introduction of epidemiological surveillance in recent years has allowed a more detailed approach to the study of community-acquired pneumonia and the development of preventive measures to stabilize the incidence. The experience of rapid detection and elimination of

Analysis of peculiarities of seasonal influenza in residents of the Altai territory

Abstract
The aim was to study the clinical features of infection caused by influenza a virus in residents of the Altai territory in the epidemic seasons 2015-2018, taking into account the antigenic characteristics of the pathogen. Material and methods . Retrospective analysis of 117

Antiretroviral therapy and efficiency of treatment of co-infection HIV/tuberculosis

Abstract
The aim of the study was to evaluate the effectiveness of antiretroviral therapy based on the analysis of blood serum lipid spectrum changes of patients with co-infection HIV/tuberculosis. Material and methods . The level of total lipids, individual fractions of the blood
Reviews

Assessment of oncological aspects in viral hepatitis C studying

Abstract
The paper is dedicated to problems of viral hepatitis C from point of view of modern oncology. The authors summarizes data demonstrated the existence of several oncological aspects of infection caused with hepatitis С virus (HСV). They considered: role of HCV

Modern view on resistance to direct antiviral drugs in the treatment of viral hepatitis C: analytical review

Abstract

This analytical review describes the actual knowledge of significance of hepatitis C virus resistance-associated substitutions to direct-acting antiviral therapy and relevance of their testing prior to therapy.

Viral hepatitis delta: an underestimated threat

Abstract
Hepatitis delta is still an unresolved global health problem. In the analytical review issues of epidemiology, diagnosis, therapy and prevention of viral hepatitis delta are considered. It is shown that the increase of migration from endemic regions, the persistence of a
Continuing medical education

Analysis of studies with vectors of arbovirus infection conducted by specialists of the United States Department of Defense

Abstract
The analysis of studies with vectors of arbovirus infections, conducted by specialists of US Department of Defense in the period 1992-2018 are presented in this review. It is shown that the researches of American military experts are large-scale, fundamental and applied in

Relevant approaches to analysis of viral genomes for biosafety

Abstract
The review summarizes the current understanding of the basic threats posed by the emergence of new human viral pathogens, in the context of emerging and re-emerging infections. On the example of the smallpox virus, influenza virus and some arboviruses the review presents the

Old and new tick-borne infections in Russia

Abstract
The article presents statistical data on the incidence of tick-borne infections in the Russian Federation and its regions. Along with the epidemiology and clinical picture of well-known tick-borne infections (ixodic tick-borne borreliosis, tick-borne viral encephalitis, tick

Features and contradictions of the legal regulation of medical confidentiality in the Russian Federation as an object of offenses of medical workers and medical organizations

Abstract
This study analyzes the peculiarities of legal regulation of one of the main objects of the offense of medical workers and medical organizations - medical secrecy. In particular, such regulations as the Federal Law «About Bases of Protection of Public Health in the

Twenty years clinical experience of pneumococcal polysaccharide vaccine in Russia in children with chronic medical conditions (information material for the preparation of the lecture)

Abstract
The review presents the data of Russian researchers on the assessment of clinical and immunological efficacy of individual vaccination against pneumococcal infection of patients with pathology of bronchopulmonary system, ENT-organs (ear, nose and throat), kidneys, with

Organizational and methodical aspects of the educational module «Spiritual and moral bases of treatment and prevention of infectious diseases»

Abstract
The article shows the importance, goals and objectives of teaching medical students the spiritual and moral aspects of the treatment and prevention of infectious diseases. Scenario of the relevant classes is modeled. The educational module analyzes the contribution of

Review of the monograph «Crimean hemorrhagic fever» (edited by Academician of the Russian Academy of Sciences G.G. Onishchenko, Corresponding Member of the Russian Academy of Sciences A.N. Kulichenko)

Abstract
Clinical tests

Clinical tests

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Reviews

News

Abstract
Announcements

Announcements

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All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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