Current issue
2 . 2015
Laboratory diagnosis
Content
Editorial

Editorial

Abstract
Continuing medical education

Biomedical PhD education – an international perspective

Abstract
The PhD, otherwise known as the doctor of philosophy or Dr. Phil., is an internationally recognized degree, indicating that the PhD graduate has received training in research under supervision. Traditionally, the PhD was the route to an academic career, with most successful

Implementation of distance learning «moodle» do interns clinical infectious diseases

Abstract
The experience of the implementation and use in training interns Department of Infectious Diseases, Faculty of Pediatrics distance learning system Moodle. The aim of distance learning is to provide students at all levels of education through the use of new information and
Scientific reviews

Modern laboratory diagnostics and biomarkers of infectious diseases

Abstract
One of the features of modern medical technologies is aiming at cost-effective, efficient, precise and less invasive diagnostic methods. From this perspective, it is important to detect pathology in the early stages of diseases, which greatly reduce need for invasive

Laboratory diagnostics of viral hepatitis

Abstract
This review describes the current approaches to laboratory diagnosis of viral hepatitis A, B, C, D and E with main focus on various serological and genetic markers of viral hepatitis infections, methods of its detection, interpretation of the results and prognostic

Aptamers: novel molecules as diagnostic markers in bacterial and viral infections?*

Abstract
Worldwide the entire human population is at risk of infectious diseases of which a high degree is caused by pathogenic protozoans, worms, bacteria, and virus infections. Moreover the current medications against pathogenic agents are losing their efficacy due to increasing

Biomarkers of Sepsis

Abstract
Sepsis remains a leading cause of death in critically ill patients, despite efforts to improve patient outcome. Thus far, no magic drugs exist for severe sepsis and septic shock. Instead, early diagnosis and prompt initial management such as early goal-directed therapy are
Original researches

Proteomic methods for diagnosis of guillain-barre syndrome associated with infectious process

Abstract
Guillain-Barre syndrome is one of the leading pathological processes among the lesions of the peripheral nervous system. It complicates the course of infectious diseases, significantly lengthens the recovery period and affects the quality of life of patients. One of the

Elastometry – modern method of hepatic fibrosis dynamic assessment in antiviral therapy for chronic hepatitis C

Abstract
Main aim of antiviral therapy for chronic hepatitis C (CHC) is prevention of of hepatic fibrosis in liver cirrhosis progression. That can be achieved in case of virus eradication. For therapy effectiveness evaluation along with virological and biochemical criteria the

Expression of TLR2 and TLR4 on lymphoid cells as a marker of infectious periodontal lesions

Abstract
A research has been carried out of expression of Tolllike receptors (TLR) of TLR2 and TLR4 on unstimulated cells of peripheral blood (neutrophils, monocytes and lymphocytes) and cells of gingival fluid at people with healthy periodontium and patients with chronic periodontal
Original articles

Characteristics of HIV variants circulating in the Russian Federation with varying viral tropism

Abstract
Tropism of HIV-1 virus is an important characteristic, which affects not only the disease progression, but also on the effectiveness of such antiretroviral drugs as CCR5 receptor antagonists. Lack of published data describing the tropism of HIV variants circulating in Russia
Practitioner’s consult

Cytokines in laboratory diagnostics*

Abstract

Boceprevir is still a relevant player in chronic hepatitis C treatment

Abstract
At the present time new methods of chronic hepatitis C treatment are rapidly developing. In connection with this there is a question about necessity of first-wave HCV first generation protease inhibitors prescription (boceprevir). This article discusses aspects of its

Meltrex® – innovative technology of new type of antiretroviral drug production for the treatment of HIV infection

Abstract
Protease inhibitors and are widely recognised as a potent tool of antiretroviral therapy. Still, many drugs of this group have numerous side effects, which can hinder adherence and therefore promote drug resistance. To improve both adherence and bioavailability there are
Clinical practice guideline

EASL Recommendations on Treatment of Hepatitis С 2015

Abstract
Clinical tests

Clinical cases

Abstract
Announcements

Announcements

Abstract

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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