Clinical case of co-infection: COVID19 and invasive meningococcal infection

AbstractIn light of the current pandemic, doctors need to raise the suspicion of concurrent SARS-CoV-2 infection with Neisseria meningitides infection. In this article we reported a case of invasive meningococcal infection in an adolescent with COVID-19. Severity of the disease depended on septic shock due to invasive meningococcal infection associated with sepsis and meningitis. The differential diagnosis with a multisystem inflammatory syndrome was tricky considering the fever, shock, meningeal symptoms, elevated levels of C-reactive protein and D-dimer, patient age, and a positive test for SARS-CoV-2. The disease outcome was good. Given the risk of invasive forms of meningococcal infection, the possible synergy of SARS-CoV-2 and Neisseria meningitidis, the complexity of differential diagnosis in patients in critical condition, immunization against meningococcal infection should be carried out according to epidemic indications, despite the COVID-19 pandemic.

Keywords:coronavirus infection; meningococcal infection; co-infection; children

Funding. The study had no sponsor support.

Conflict of interest. The authors declare no conflict of interest.

Contribution. The concept and writing of the text, approval of the final version of the article – Samodova O.V.; collection and processing of material, making edits, making a list of references – Rogushina N.L.; editing the text, making edits, making the article according to the requirements of the journal – Krieger E.A.

For citation: Samodova O.V., Krieger E.A., Rogushina N.L. Clinical case of co-infection: COVID19 and invasive meningococcal infection. Infektsionnye bolezni: novosti, mneniya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2022; 11 (3): 151–5. DOI: https://doi.org/10.33029/2305-3496-2022-11-3-151-155

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CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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