Clinical and laboratory characteristics of new coronaviral infection (COVID-19) in children

Abstract

Another rise in the incidence of a new coronavirus infection (COVID-19), due to the penetration of the SARS-CoV-2 delta strain into Russia in the second half of April 2021, is characterized by rapid spread, severe course in adults and an increase in cases of the disease among children.

The aim of the work is to assess the clinical and laboratory parameters of a new coronavirus infection (COVID-19) in children.

Material and methods. The results of clinical and laboratory examination and complex therapy of 95 children with moderate and severe forms of COVID-19, hospitalized in the Republican Clinical Infectious Diseases Hospital in Ufa from May to September 2021, are presented.

Results. The anamnesis of the disease and life, epidemiological, clinical and laboratory, instrumental data obtained during the examination of children with COVID-19 in the course of the disease were studied. Among the clinical manifestations in children, symptoms of acute respiratory infection (37.9±4.98%), pneumonia without respiratory failure (26.3±4.52%), pneumonia with acute respiratory failure (33.7±4.85%). In 2 patients of the first months of life (2.1±1.47%), against the background of a aggravated premorbid background, immunodeficiency, COVID-19 proceeded in an extremely severe form with a fatal outcome.

Conclusion. The clinical manifestations of COVID-19 are similar in children and adults, but differ in the frequency of respiratory symptoms. A severe course with a fatal outcome was registered in children in the first months of life with a burdened premorbid background.

Keywords:COVID-19; children; infants; clinic; diagnostics; therapy components

Funding. The study did not have financial support.

Conflict of interest. The authors declare no conflict of interest.

Contribution. Concept and design – Murzabaeva R.T., Valishin D.A.; data collection – Murzabaeva R.T., Abrashina N.A., Murzagaleeva L.V., Valishina A.D.; statistical processing – Abrashina N.A., Valishin D.A., Murzagaleeva L.V.; text writing, design – Murzabaeva R.T., Abrashina N.A., Valishina A.D.; editing – Valishin D.A., Murzabaeva R.T.

For citation: Murzabaeva R.T., Valishin D.A., Abrashina N.A., Murzagaleeva L.V., Valishina A.D. Clinical and laboratory characteristics of new coronaviral infection (COVID-19) in children. Infektsionnye bolezni: novosti, mneniya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2022; 11 (2): 32–7. DOI: https://doi.org/10.33029/2305-3496-2022-11-2-32-37

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CHIEF EDITOR
CHIEF EDITOR
Yushchuk Nikolay Dmitrievich
Academician of the Russian Academy of Sciences, Professor, head of the Infectious Diseases and Epidemiology Department, President of the Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Board member of the National Scientific Infectiologists? Society.
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