Features of the course of labor in patients with concomitant acute intestinal infections at full-term pregnancy
AbstractOccupying one of the leading positions in the structure of infectious diseases, acute intestinal infections (AII) affect people of all age groups. The pathogens that occupy leading positions differ in different age groups of people. There is practically no information about the features of the etiology and clinical course of acute intestinal diseases in women of reproductive age according to domestic and foreign literature. Individual works that reveal this problem are devoted to certain pathogens of intestinal infection and do not cover the entire possible range of microorganisms.
Aim: to evaluate the features of the course of acute intestinal infections in pregnant and non-pregnant women of reproductive age.
Material and methods. The study included 90 patients aged 19 to 39 years with a confirmed diagnosis of AII, who were treated in the St. Petersburg Clinical Infectious Diseases Hospital named after S.P. Botkin in 2017-2019. All the women were divided into 2 groups. The main group included 60 women delivered in the obstetric department at full-term gestation, the comparison group included 30 non-pregnant women with AII, who were comparable to the main group in terms of age and concomitant pathology. The exclusion criteria were the presence of acute surgical pathology and other acute inflammatory diseases of any localization, except for the manifestations of AII.
Results. The spectrum of pathogens of AII in patients of the age group of 19-39 years during pregnancy and outside of it does not differ and is represented, for the most part, by conditionally pathogenic flora. Despite the uniformity of the flora that causes AII, the clinical manifestations of this disease are different in pregnant and non-pregnant women. Diarrhea in combination with vomiting was observed more often in pregnant women, a combination of fever and gastrointestinal lesions, as well as hemocolitis - more often in non-pregnant patients. Indicators of inflammatory markers in patients with AII are higher in pregnant women.
Conclusion. Pregnancy, with the physiological changes that occur during it in all the organs and systems of a woman, contributes to a change in the nature of the course of AII.
Keywords:pregnancy, acute intestinal infection, reproductive age
Funding. The work was carried out at the personal expense of the author's team.
Conflict of interest. The authors declare that there is no conflict of interest.
Сontribution. The authors of the article participated equally in the preparation of its manuscript for publication in accordance with the Vancouver Recommendations on the authorship of articles.
For citation: Kovalchuk A.S., Lioznov D.A., Popov E.N., Sudakov D.S. Features of the course of labor in patients with concomitant acute intestinal infections at full-term pregnancy. Infektsionnye bolezni: novosti, mneniya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2021; 10 (4): 76-80. DOI: https://doi.org/10.33029/2305-3496-2021-10-4-76-80 (in Russian)
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