REFERENCES
1. Federal Scientific Center for the Prevention and Combat of AIDS of the Public Office of the Central Scientific Research Institute Rospotrebnadzor. Reference on HIV infection in the Russian Federation at 2020. 2020: 2 p. (in Russian)
2. Ladnaya N.N., Pokrovsky V.V., Dement’eva L.A., et al. The development of the HIV epidemic in Russia in 2017. In: Materials of the International conference «Actual problems of HIV». Saint Petersburg, 2018: 3-9. (in Russian)
3. Russian Federation Drug Situation Report, 2018. State Anti-Drug Committee. Moscow, 2019: 49 p. URL: https://media.mvd.ru/files/application/1628743 (in Russian)
4. Lucas G.M., Griswold M., Gebo K.A., Keruly J., Chaisson R.E., Moore R.D. Illicit drug use and HIV-1 disease progression: a longitudinal study in the era of highly active antiretroviral therapy. Am J Epidemiol. 2006; 163 (5): 412-20. DOI: https://doi.org/10.1093/aje/kwj059
5. Roy S., Ninkovic J., Banerjee S., Charboneau R.G., Das S., Dutta R., et al. Opioid drug abuse and modulation of immune function: consequences in the susceptibility to opportunistic infections. J Neuroimmune Pharmacol. 2011; 6 (4): 442-65. DOI: https://doi.org/10.1007/s11481-011-9292-5
6. Arnsten J.H., Demas PA., Grant R.W., Gourevitch M.N., Farzadegan H., Howard A.A., et al. Impact of active drug use on antiretroviral therapy adherence and viral suppression in HIV-infected drug users. J Gen Intern Med. 2002; 17 (5): 377-81. DOI: https://doi.org/10.1046/j.1525-1497.2002.10644.x
7. Nair M.P.N., Schwartz S.A., Polasani R., Hou J., Sweet A., Chadha K.C. Immunoregulatory effects of morphine on human lymphocytes. Clin Diagn Lab Immunol. 1997; 4 (2): 127-32. PMID: 9067644.
8. Noel R.J., Rivera-Amill V., Buch S., Kumar A. Opiates, immune system, acquired immunodeficiency syndrome, and nonhuman primate model. J Neurovirol. 2008; 14 (4): 279-85. DOI: https://doi.org/10.1080/13550280802078209
9. Meng J., Yu H., Ma J., Wang J., Banerjee S., Charboneau R., et al. Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner. PLoS One. 2013; 8: e54040. DOI: https://doi.org/10.1371/journal.pone.0054040
10. Eisenstein T.K. The role of opioid receptors in immune system function. Front Immunol. 2019; 10: 2904. DOI: https://doi.org/10.3389/fimmu.2019.02904
11. Brenchley J.M., Douek D.C. The mucosal barrier and immune activation in HIV pathogenesis. Curr Opin HIV AIDS. 2008; 3: 356-61. DOI: https://doi.org/10.1097/C0H.0b013e3282f9ae9c
12. Nowroozalizadeh S., Mansson F., da Silva Z., Repits J., Dabo B., Pereira C., et al. Microbial translocation correlates with the severity of both HIV-1 and HIV-2 infections. J Infect Dis. 2010; 201 (8): 1150-4. DOI: https://doi.org/10.1086/651430
13. Marchetti G., Tincati C., Silvestri G. Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4+ cell count. AIDS. 2011; 25 (11): 1385-94. DOI: https://doi.org/10.1128/CMR.00050-12
14. Kholodnaya A.N., Lioznov D.A., Blokhina E.A., Yaroslavtseva T.S., Krupitskiy E.M. Levels of plasma soluble CD14 in HIV-infected opiate users. Zhurnal infektologii [Journal of Infectology]. 2018; 10 (1): 47-54. DOI: https://doi.org/10.22625/2072-6732-2018-10-1-47-54 (in Russian)
15. Kholodnaya A.N., Lioznov D.A., Nikolaenko S.L., Blokhin E.A., Yaroslavtseva T.S., Krupitsky E.M. Assessment of systemic inflammation markers in HIV-infected opiate users. VICH infektsiya i immunosupressii [HIV Infection and Immunosuppression]. 2018; 10 (2): 90-5. DOI: https://doi.org/10.22328/2077-9828-2018-10-2-90-95 (in Russian)
16. Kholodnaya A.N., Lioznov D.A., Nikolaenko S.L., Blokhin E.A., Yaroslavtseva T.S., Krupitsky E.M. Bacterial translocation and systemic inflammation under the conditions of comorbidity pathogenesis of HIV-infection and opioid abuse. Infektsionnye bolezni: novosti, mneniya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2019; 8 (3): 7-13. DOI: https://doi.org/10.24411/2305-3496-2019-13001 (in Russian)
17. Krastinova E., Lecuroux C., Leroy C., Seng R., Cabie A., Rami A., et al. High soluble CD14 levels at primary HIV-1 infection predict more rapid disease progression. J Infect Dis. 2015; 212: 909-13. DOI: https://doi.org/10.1093/infdis/jiv145
18. Sandler N.G., Wand H., Roque A., Law M., Nason M.C., Nixon D.E., et al.; INSIGHT SMART Study Group. Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis. 2011; 203 (6): 780-90. DOI: https://doi.org/10.1093/infdis/jiq118
19. Karris M.Y., Kao Y.T., Patel D., Dawson M., Woods S.P., Vaida F., et al. Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection. AIDS. 2014; 28 (6): 841-9. DOI: https://doi.org/10.1097/QAD.0000000000000149
20. Meng J., Banerjee S., Zhang L., Sindberg G., Moidunny S., Li B., et al. Opioids impair intestinal epithelial repair in HIV-infected humanized mice. Front Immunol. 2020; 10: 2999. DOI: https://doi.org/10.3389/fimmu.2019.02999
21. Petrosyan T.R., Shakhmardanov M.Z. HIV infection and drug use. Epidemiologiya i infektsionnye bolezni [Epidemiology and Infectious Diseases]. 2018; (2): 60-7. (in Russian)
22. Eisenstein T.K., Rahim R.T., Feng P., Thingalaya N.K., Meis-sler J.J. Effects of opioid tolerance and withdrawal on the immune system. J Neuroimmune Pharmacol. 2006; 1 (3): 237-49. DOI: https://doi.org/10.1007/s11481-006-9019-1
23. Govitrapong P., Suttitum T., Kotchabhakdi N., Uneklabh T. Alterations of immune functions in heroin addicts and heroin withdrawal subjects. J Pharmacol Exp Ther. 1998; 286: 883-9. PMID: 9694946.
24. Feng P., Truant A.L., Meissler J.J Jr, Gaughan J.P., Adler M.W., Eisen-stein T.K. Morphine withdrawal lowers host defense to enteric bacteria: spontaneous sepsis and increased sensitivity to oral Salmonella enterica serovar Typhimurium infection. Infect Immun. 2006; 74 (9): 5221-6. DOI: https://doi.org/10.1128/IAI.00208-06
25. Lester R.T., Yao X.D., Ball T.B., McKinnon L.R., Omange W.R., Kaul R., et al. HIV-1 RNA dysregulates the natural TLR response to subclinical en-dotoxemia in Kenyan female sex-workers. PLoS One. 2009; 4: e5644. DOI: https://doi.org/10.1371/journal.pone.0005644
26. Wang X., Liu J., Zhou L., Ho W.-Z. Morphine withdrawal enhances HIV infection of macrophages. Front Immunol. 2019; 10: 2601. DOI: https://doi.org/10.3389/fimmu.2019.02601
27. FunderburgN.T., Mayne E., Sieg S.F., Asaad R., JiangW., Kalinowska M., et al. Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. Blood. 2010; 115 (2): 161-7. DOI: https://doi.org/10.1182/blood-2009-03-210179
28. Neema N., Singh R., Sharma A., Das B.K., Vajpayee M. Comparative evaluation of microbial translocation products (LPS, sCD14, IgMEndocab) in HIV-1 infected Indian Individuals. Microb Pathog. 2017; 111: 331-7. DOI: https://doi.org/10.1016/j.micpath.2017.08.004