Extracellular vesicles (exosomes) and parasitic infections. Part 2. The role of exosomal microvesicular structures in parasitic diseases
AbstractWhen the host and parasite interact, exosomal microvesicular structures (EMVS) mediates mutual communication, transfers virulence factors and other effector molecules, and regulates the expression of various pathogen and host genes. A better understanding of the mechanisms of formation and functioning of EMVS can induce new ideas for further development of molecular diagnostic biomarkers, vaccines, and therapeutic methods for parasitic, and perhaps other disease.
Keywords:parasites, exosomal microvesicular structures, parasitic pathology, diagnosis, immunotherapy, vaccination
Funding. The study was not sponsored.
Conflict of interest. The authors declare that there is no conflict of interest.
Contribution. Research concept - Shenderov B.A., research design - Kuznetsova K.Yu., Sergiev V.P.; material collection - Shen-derov B.A., Sergiev V.P.; material processing - Kuznetsova K.Yu.; text writing - Shenderov B.A., Kuznetsova K.Yu.; editing - all authors.
For citation: Shenderov B.A., Kuznetsova K.Yu., Sergiyev V.P. Extracellular vesicles (exosomes) and parasitic infections. Part 2. The role of exosomal microvesicular structures in parasitic diseases. Infektsionnye bolezni: novosti, mneniya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2021; 10 (1): 66-74. DOI: https://doi.org/10.33029/2305-3496-2021-10-1-66-74 (in Russian)
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