Some features of the treatment of acute intestinal infections in adults and children

Abstract

Acute intestinal infections with severe diarrhea syndrome constitute a significant part of hospitalized patients with infectious diseases, which necessitates the use of enterosorbents.

The aim: to analyze the effectiveness of the use of the Polysorb MP enterosorbent (active ingredient: colloidal silicon dioxide), in comparison with other enterosorbents, as a component of the treatment of acute intestinal infections, using the example of the time period for eliminating pain and dyspeptic syndromes.

Material and methods. 62 cases of acute intestinal infections were analyzed in the Penza Regional Clinical Center for Specialized Medical Assistance. The diagnosis of OCI was established on the basis of anamnestic and clinical data. The diagnosis was confirmed by bacteriological inoculation of feces, by PCR for the presence of genetic material of causative agents of acute intestinal infections. Statistical processing of research materials was carried out using methods of variation statistics.

Results. The use of the Polysorb MP as part of the complex therapy of acute intestinal infections agents contributes to a more rapid regression of the clinical manifestations of the disease: the pain syndrome was stopped, on average, within 1-3 days, the dyspeptic syndrome was stopped within 1-6 days (when using another enterosorbent, from 2 to 6 days and from 2 to 7 days, respectively).

Conclusion. Enterosorbent Polysorb MP is effective in adults and children in the treatment of acute intestinal infections of various etiologies, is convenient to use and safe.

Keywords:acute intestinal infections, treatment, enterosorbents, Polisorb MP (Silicium dioxide colloidal)

Funding. The study had no sponsor support.

Conflict of interests. The authors declare no conflict of interests.

Contribution. The concept and design of the study - Krasnova L.I., Baranova I.P., Kurmaeva D.Yu., Popilov M.A.; collection and processing of material - Krasnova L.I., Dubinovskaya E.V.; statistical processing - Dubinovskaya E.V.; writing the text - Krasnova L.I., Baranova I.P., Dubinovskaya E.V.; editing - Baranova I.P.; approval of the final version of the article - Baranova I.P., Kurmaeva D.Yu.

For citation: Krasnova L.I., Baranova I.P., Dubinovskaya E.V., Kurmayeva D.Yu., Popilov M.A. Some features of the treatment of acute intestinal infections in adults and children. Infektsionnye bolezni: novosti, mneniya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2020; 9 (4): 92-7. DOI: https://doi.org/10.33029/2305-3496-2020-9-4-92-97 (in Russian)

References

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CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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