To the content
1 . 2012

Antiretroviral therapy in patients with HIV-infections and tuberculosis

Abstract

Modern approaches to using the ART in patients with HIV infection and tuberculosis are presented in article. Prescriptions to start the ART, optimum terms of using the ART and a choice of the most effective and safe scheme of ART, taking into account medicinal interactions and co-morbidity, – the key points in therapeutic approach at HIV infection and tuberculosis combination. Rifampicin using in PTT scheme essentially narrows a range of antiretroviral drugs. Inclusion of raltegravirin the doubled dose in ART scheme structure showed good efficiency and safety of ART in HIVinfected patients receiving treatment by rifampicin.

Replacement in PTT scheme of rifampicin on rifabutin simplifies making decision about ART scheme structure.

Keywords:HIV-infection, tuberculosis, ART, raltegravir, rifampicin, rifabutin

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)
Journals of «GEOTAR-Media»