The hypothesis of epidemic welfare for SARS-CoV-2 in Russia

AbstractCoronavirus infection is a thunderbolt for the wholeworld with a high morbidity and mortality rate among certain age groups. The proportion of cases in Russia is much less in comparison with other countries. The reason for the low susceptibility to SARS-CoV-2 remains a mystery and will be the subject of subsequent discussions. In the article the materials of the studies carried out at the I.I. Mechnikov Research Institute of Vaccines and Sera, concerning the study of adjuvant influenza vaccines are presented. Based on the results of assessment of the molecular and cellular mechanisms induced by various influenza vaccines, an immunological hypothesis is put forward for the influence of nonspecific antiviral effect of mass vaccination using national immunoadjuvant vaccines on the decrease of susceptibility of the Russian population to coronavirus infection SARS-CoV-2.

Keywords:adjuvants, influenza vaccine, innate and adaptive immunity, SARS-CoV-2

Funding. The study had no sponsor support.

Conflict of interest. The author declares no conflict of interest.

For citation: Kostinov M.P. The hypothesis of epidemic welfare for SARS-CoV-2 in Russia. Infektsionnye bolezni: novosti, mne-niya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2020; 9 (2): 50-6. DOI: 10.33029/2305-3496-2020-9-2-50-56 (in Russian)

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CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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