Differential diagnostics of the Crimean hemorrhagic fever and measles at the modern stage

Abstract

The paper presents modern differential diagnostic criteria for the diagnosis of Crimean hemorrhagic fever caused by the Congo virus (CHF), and measles, allowing timely diagnosis and early adequate therapy. Specific epidemiological signs were identified that could indicate the presence of CHF, suction or contact with a tick, detection of a specific primary affect, spring-summer season of fever (100%), prevalence among rural people of working age (81.6%), high risk of infection for people of certain professions, the fact of going outdoors in urban population.

It was established that with measles, the incidence is higher in the autumn-winter period, a tendency to "grow" measles in people aged 15-30 years (74.6%), the prevailing number of cases is in urban population (76.6%). The main differential diagnostic criteria of CHF and measles are highlighted.

The features of intoxication, catarrhal and hemorrhagic syndromes, characteristic organ lesions and early changes in peripheral blood were revealed.

Keywords:Crimean hemorrhagic fever, hemorrhagic syndrome, ticks, primary affect, measles, catarrhal syndrome, rose-papular rash, enanthema, Belsky-Filatov-Koplik spots

Funding. The scientific article was carried out as part of a state assignment of the Ministry of Health of the Russian Federation for research, developmental and technological work "Modern clinical and laboratory features of the clinical course of arbovirus infections" No. AAAA-A18-118020190038-1 February 1, 2018.

Conflict of interests. The authors declare no conflict of interests.

For citation: Mirekina E.V., Yarmukhamedova N.A., Galimzyanov Kh.M., Cherenova L.P. Differential diagnostics of the Crimean hemorrhagic fever and measles at the modern stage. Infektsionnye bolezni: novosti, mneniya, obuchenie [Infectious Diseases: News, Opinions, Training]. 2020; 9 (1): 103-8. doi: 10.33029/2305-3496-2020-9-1-103-108 (in Russian)

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CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)

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